Encephalitis associated with autoantibodies binding to g-aminobutyric acid-A, g-aminobutyric acid-B and glycine receptors: immunopathogenic mechanisms and clinical characteristics
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Gamma aminobutyric acid and glycine receptors in the nucleus
Gamma aminobutyric acid and glycine receptors in the nucleus ambiguus mediate 1 tachycardia elicited by chemical stimulation of the hypothalamic arcuate nucleus 2 3 Vineet C. Chitravanshi, Kazumi Kawabe and Hreday N. Sapru 4 5 Department of Neurological Surgery, Rutgers New Jersey Medical School, 185 South Orange 6 Avenue, Newark, NJ 07103, USA 7 8 9 10 Short title: Arcuate nucleus: heart rate ...
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In the present study, we provide evidence that the a9 nicotinic acetylcholine receptor (nAChR) shares pharmacological properties with members of the Cys-loop family of receptors. Thus, the type A g-aminobutyric acid receptor antagonist bicuculline, the glycinergic antagonist strychnine, and the type 3 serotonin receptor antagonist ICS-205,930 block ACh-evoked currents in a9-injected Xenopus lae...
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Benzodiazepine potentiation of g-aminobutyric acid (GABA) neurotransmission is associated with the presence of a gamma-2 subunit in the GABAA receptor. A method was developed to modify the gamma-2 subunit expression in adult rat brain. Unilateral intracerebroventricular (i.c.v.) infusion of a 17-base phosphorothioate-modified antisense oligodeoxynucleotide (ASO) was performed every 12 hr for 3 ...
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Activation of protein kinase C (PKC) by phorbol 12-myristate 13-acetate induced a continuous decrease in the g-aminobutyric acid (GABA)-activated current amplitude from recombinant GABA receptors (formed by r1 or abg subunits) expressed in Xenopus oocytes. This decline was due to internalization of receptors from the plasma membrane as confirmed by a decrease in surface fluorescence with green ...
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Using human g-aminobutyric acid type A (GABAA) receptor subunit combinations, expressed in cell lines and Xenopus laevis oocytes, the pharmacology of a number of ligands interacting directly with the GABA recognition site has been studied in [H]muscimol binding and electrophysiologically. The binding affinity of GABAA agonist and antagonist ligands showed small but statistically significant dep...
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ژورنال
عنوان ژورنال: Neuroimmunology and Neuroinflammation
سال: 2015
ISSN: 2347-8659
DOI: 10.4103/2347-8659.170633